lactobacillus
3 interactions related to lactobacillus
kefir + antibiotics
Antibiotics can kill the live Lactobacillus and yeast cultures in kefir if both are consumed at the same time, reducing the probiotic benefit. Spacing kefir 2-3 hours away from the antibiotic dose preserves the live cultures and helps replenish gut microbes during and after the course.
probiotics + immunosuppressants
Live probiotic bacteria can translocate across the gut wall and cause bacteremia, endocarditis, or sepsis in patients whose immune systems are pharmacologically suppressed (e.g., calcineurin inhibitors, mTOR inhibitors, corticosteroids, mycophenolate). Multiple case reports document Lactobacillus and Bifidobacterium bloodstream infections in solid-organ and stem-cell transplant recipients.
lactobacillus + tacrolimus
Tacrolimus is a calcineurin-inhibitor immunosuppressant used after solid-organ transplant. Lactobacillus species have caused bacteremia, endocarditis, and liver abscess in transplant recipients on tacrolimus, including a published case of recurrent Lactobacillus rhamnosus bacteremia in a renal transplant patient.