1 interaction related to korsakoff
Alcohol depletes thiamine (vitamin B1) at multiple levels — reducing its absorption from the gut, impairing the liver's ability to convert it to its active form, and increasing how much is lost in urine. In heavy drinkers this can lead to Wernicke encephalopathy, a neurologic emergency, which if untreated may progress to Korsakoff syndrome, a chronic and often irreversible memory disorder.
