inflammation
4 interactions related to inflammation
curcumin + boswellia
Curcumin and boswellia act on complementary anti-inflammatory pathways (NF-kB/prostaglandins and 5-LOX/leukotrienes), and a randomized placebo-controlled trial found the combination eased knee osteoarthritis symptoms more than curcumin alone.
curcumin + ginger
Curcumin and ginger share overlapping anti-inflammatory mechanisms (COX-2 and NF-kB inhibition), with ginger adding 5-LOX blockade that curcumin lacks. The combination is favourable and complementary, with both contributing mild antiplatelet potential worth checking before combining with blood thinners.
omega-3 + curcumin
Omega-3 fatty acids (EPA and DHA) and curcumin lower inflammation through complementary pathways — omega-3s remodel cell membranes and generate specialized pro-resolving mediators, while curcumin inhibits NF-kB and downstream inflammatory cytokine signaling. Human trials in migraine patients show the combination can reduce inflammatory markers more than either alone.
boswellia + omega-3
Boswellic acids inhibit 5-lipoxygenase to reduce pro-inflammatory leukotrienes, while EPA and DHA from omega-3s lower the arachidonic acid available to inflammatory enzymes and serve as substrates for specialized pro-resolving mediators (resolvins, protectins) that help switch inflammation off. The two act at different steps of the same lipid cascade, giving complementary anti-inflammatory coverage. Evidence in joint pain is modest but consistent.