1 interaction related to immunosuppression
Tacrolimus is a calcineurin-inhibitor immunosuppressant used after solid-organ transplant. In immunosuppressed transplant recipients, Lactobacillus probiotic organisms can cross the gut wall and cause bloodstream infection. Published case reports document Lactobacillus rhamnosus bacteremia in renal transplant patients on tacrolimus, and many probiotic strains are intrinsically vancomycin-resistant, making treatment harder.
