hyperparathyroidism
2 interactions related to hyperparathyroidism
hydrochlorothiazide + calcium
Thiazide diuretics increase renal tubular reabsorption of calcium and reduce urinary calcium excretion, which is therapeutically useful for preventing kidney stones and reducing bone loss. However, this calcium-sparing effect can produce hypercalcemia when combined with high-dose calcium supplements, vitamin D, or in patients with underlying primary hyperparathyroidism.
vitamin d + parathyroid hormone test
Vitamin D supplementation does not chemically interfere with the parathyroid hormone (PTH) assay itself, but it physiologically suppresses PTH secretion by raising serum 25-hydroxyvitamin D and calcium levels. A PTH drawn after starting or adjusting vitamin D can therefore look lower than the patient's true baseline, complicating workup of suspected primary hyperparathyroidism or vitamin D deficiency.