hydration
3 interactions related to hydration
electrolytes + carbohydrates
Sodium and glucose share the SGLT1 cotransporter in the small intestine; their co-ingestion drives faster water absorption than either alone (the basis of oral rehydration therapy). Carbohydrate also delays gastric emptying slightly while providing exercise fuel.
hyaluronic acid + collagen
Hyaluronic acid and collagen are the two dominant structural components of the extracellular matrix in skin and synovial fluid — collagen provides tensile strength while hyaluronic acid binds water and provides cushioning. Oral collagen peptides have been shown to upregulate fibroblast production of hyaluronic acid, and clinical trials of combined oral HA plus collagen formulations show additive improvements in skin hydration and elasticity.
coconut water + spironolactone
Coconut water is naturally high in potassium (roughly 600 mg per cup) and is often consumed in large volumes for hydration. Spironolactone is a potassium-sparing diuretic that reduces renal potassium excretion. Regular high-volume coconut water consumption with spironolactone can cause hyperkalemia, including cases reported in the medical literature.