hrt
2 interactions related to hrt
hrt + soy isoflavones
The idea that soy isoflavones add an extra estrogen dose on top of HRT is not supported by the best human evidence; pooled randomized-trial data show isoflavones do not meaningfully raise estradiol, suppress FSH, or thicken the endometrium in postmenopausal women.
hrthormone replacement therapysoy isoflavonesgenisteindaidzeinphytoestrogenmenopausebreast cancer
smoking + hrt
Smoking speeds up how the liver breaks down estradiol, lowering circulating estrogen and reducing the effectiveness of oral hormone replacement therapy. It also adds to the blood-clot risk that oral HRT already carries.
smokinghrthormone replacement therapyestradiolmenopausecyp450transdermalvteestrogen metabolismbone loss