1 interaction related to hormone replacement
Dong quai (Angelica sinensis) shows estrogen-agonist activity in laboratory studies and can stimulate the growth of estrogen receptor-positive breast cancer cells in cell and animal models. Taken alongside prescribed estrogen, it adds an extra, unmeasured estrogenic signal in hormone-sensitive tissues. Dong quai also contains coumarin compounds that can add to bleeding risk, with one case report describing potentiation of warfarin.