herb interaction
3 interactions related to herb interaction
losartan + licorice
Glycyrrhizin in licorice mimics aldosterone, causing renal sodium and water retention and potassium loss. This pseudoaldosteronism raises blood pressure and counteracts losartan's antihypertensive effect, while also producing hypokalemia that can cause weakness and arrhythmia.
losartan + hawthorn
Hawthorn produces modest blood pressure lowering (roughly 5 to 11 mmHg systolic in clinical trials) through vasodilation and mild ACE-like activity. Combined with losartan, the additive effect could occasionally cause hypotension or dizziness, particularly in people on multiple antihypertensives or those starting hawthorn at high doses.
lisinopril + licorice
Glycyrrhizin in licorice mimics aldosterone, causing the kidneys to retain sodium and water and excrete potassium. This raises blood pressure and directly opposes lisinopril's antihypertensive effect, while also driving hypokalemia that can complicate other cardiovascular risks.