heart
3 interactions related to heart
dairy + digoxin
Dairy is a dietary source of calcium, and calcium status modestly influences how digoxin acts on the heart. The dietary-dairy effect is minor on its own; the more relevant scenario is large stacked calcium loads (dairy plus supplements plus calcium-containing antacids) or intravenous calcium in a hospital setting. Milk proteins may also slightly reduce digoxin absorption from oral doses, but the effect is small and usually not clinically meaningful.
salt substitute + spironolactone
Most salt substitutes replace ordinary table salt with potassium chloride, so they act as concentrated potassium supplements. Spironolactone is a potassium-sparing diuretic that reduces how much potassium the kidneys excrete. Using the two together can drive potassium high enough to cause dangerous, sometimes life-threatening heart rhythm problems (hyperkalemia).
bananas + spironolactone
Bananas are a well-known high-potassium food, and spironolactone is a potassium-sparing diuretic that makes the kidneys hold onto potassium. Eating large amounts of bananas (and other high-potassium foods) while taking spironolactone can push blood potassium too high (hyperkalemia), which in serious cases can disturb the heart's rhythm.
