1 interaction related to hangover
N-acetylcysteine (NAC) is a precursor to glutathione, the antioxidant the liver uses to neutralize acetaldehyde, the toxic intermediate of alcohol metabolism. The mechanism is plausible and animal studies show reduced alcohol-induced oxidative stress, but human trials are mixed-to-negative: the best controlled studies found no meaningful effect on hangover symptoms or oxidative markers. NAC does not protect against the cumulative harms of drinking.
