graves disease
2 interactions related to graves disease
methimazole + iodine
Methimazole blocks new thyroid hormone synthesis but does not prevent the gland from using iodide already inside it. Adding a large iodine load (kelp, iodine drops, iodine-containing contrast, amiodarone) can fuel hormone production, blunt methimazole's effect, and in some cases precipitate worsening hyperthyroidism or thyroid storm.
methimazoleiodinehyperthyroidismgraves diseasekelpcontrastamiodaronethyroid storm
biotin + thyroid stimulating hormone test
High-dose biotin interferes with biotin-streptavidin-based immunoassays used to measure TSH, free T3, free T4, and thyroglobulin, producing a falsely low TSH and falsely elevated free thyroid hormones, a pattern that mimics Graves' disease. Patients have been incorrectly diagnosed with hyperthyroidism and started on antithyroid drugs because of biotin interference.
biotinvitamin b7tshthyroid function testfree t4lab interferencegraves diseaseimmunoassay