1 interaction related to glucosamine
MSM (methylsulfonylmethane) provides bioavailable sulfur required for the synthesis of glycosaminoglycans and connective tissue, which complements glucosamine's role as a substrate for proteoglycan production. A 12-week randomized trial in knee osteoarthritis found the combination of MSM plus glucosamine produced greater reductions in pain and swelling than either supplement alone.