1 interaction related to ginkgotoxin
Ginkgo biloba can induce CYP2C19, an enzyme involved in clearing phenytoin, which may lower phenytoin blood levels and raise the risk of breakthrough seizures. A published fatal case report described subtherapeutic phenytoin and valproate levels in a patient who had been self-administering ginkgo. Ginkgo also carries its own seizure-related signal. If you take phenytoin, avoid ginkgo and review any supplement changes with your doctor or pharmacist.
