ginger
3 interactions related to ginger
curcumin + ginger
Curcumin and ginger share overlapping anti-inflammatory mechanisms (COX-2 and NF-kB inhibition), with ginger adding 5-LOX blockade that curcumin lacks. The combination is favourable and complementary, with both contributing mild antiplatelet potential worth checking before combining with blood thinners.
warfarin + ginger
Ginger has a mild antiplatelet effect that can add to warfarin's anticoagulant effect. Case reports describe a rise in INR after a person on stable warfarin started a daily ginger supplement, with the INR returning to range once the supplement was stopped. Ginger used in cooking and the occasional ginger tea is a food-level exposure and is generally considered safe.
ginger tea + metformin
Ginger (Zingiber officinale) has modest blood-glucose-lowering activity in randomized trials in type 2 diabetes, mainly improving fasting glucose and HbA1c. Combined with metformin the effect is generally additive rather than dangerous. Metformin alone rarely causes hypoglycemia, so the practical concern is small; the risk of a true low rises mainly when ginger is layered onto insulin or an insulin-secreting drug.
