gabapentinoid
2 interactions related to gabapentinoid
alcohol + pregabalin
Pregabalin (Lyrica) and alcohol are both central nervous system depressants with additive effects on sedation, coordination, and respiratory drive. The FDA's 2019 Drug Safety Communication warned that pregabalin can cause life-threatening respiratory depression when combined with CNS depressants such as alcohol, particularly with opioids or in patients with lung disease.
alcoholpregabalinlyricagabapentinoidrespiratory depressioncns depressantopioidfda warningdrug interaction
alcohol + gabapentin
Gabapentin and alcohol are both central nervous system depressants. The FDA issued a 2019 Drug Safety Communication warning that gabapentin can cause serious, potentially fatal respiratory depression when combined with CNS depressants including alcohol, particularly in older adults and patients with respiratory disease.
alcoholgabapentinneurontingabapentinoidrespiratory depressioncns depressantopioiddrug interactionfda warning