gabapentin
2 interactions related to gabapentin
gabapentin + antacids
Aluminum- and magnesium-containing antacids reduce the amount of gabapentin absorbed when the two are taken at the same time. The effect is mechanical (the antacid interferes with gabapentin's intestinal uptake) rather than acid- or pH-related, so it can be largely avoided by spacing the two doses a couple of hours apart and taking gabapentin after the antacid.
gabapentinneurontinantacidsaluminum hydroxidemagnesium hydroxidemaaloxabsorptionbioavailability
alcohol + gabapentin
Gabapentin and alcohol are both central nervous system depressants. Combining them increases drowsiness, dizziness, impaired coordination, and the risk of serious, potentially life-threatening respiratory depression, especially in older adults and people with lung disease, sleep apnea, kidney impairment, or who take opioids or other sedatives.
alcoholgabapentinneurontingabapentinoidrespiratory depressioncns depressantopioiddrug interactionfda warning