1 interaction related to free t4
High-dose biotin can interfere with the biotin-streptavidin immunoassays many labs use to measure TSH, free T4, free T3, and thyroglobulin. The result is a falsely low TSH alongside falsely elevated free thyroid hormones, a pattern that can mimic Graves' disease. Published case reports describe patients who were wrongly diagnosed with hyperthyroidism, and started on antithyroid drugs, because of biotin interference that resolved once biotin was stopped.
