1 interaction related to fibrate
Red yeast rice supplies monacolin K, a compound chemically identical to the statin lovastatin. Combining it with gemfibrozil, a fibrate, can add up to serious muscle injury. The fibrate is itself toxic to muscle and also raises circulating statin levels by interfering with how the statin is cleared, so the two effects stack toward myopathy and, in the worst case, rhabdomyolysis with kidney injury.
