1 interaction related to fenugreek
Fenugreek (Trigonella foenum-graecum) contains coumarin-related compounds and has shown anticoagulant activity in laboratory studies. A published case report describes a rise in INR when a boldo-fenugreek combination product was added to stable warfarin therapy, with INR normalizing on discontinuation and rising again on rechallenge. The evidence is limited to that single case plus mechanistic plausibility, so the interaction is treated as plausible rather than firmly established.