effexor
2 interactions related to effexor
venlafaxine + st. john's wort
Venlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI). St. John's wort independently inhibits serotonin (and to a lesser extent norepinephrine and dopamine) reuptake. Combining them can drive a sharp rise in synaptic serotonin and trigger serotonin syndrome, and St. John's wort can also alter venlafaxine pharmacokinetics through CYP3A4 induction.
venlafaxineeffexorsnrist johns wortserotonin syndromehypericumantidepressantcyp3a4contraindication
alcohol + venlafaxine
Venlafaxine (Effexor) is an SNRI that, like other antidepressants, has additive CNS-depressant effects with alcohol. The FDA-approved label warns patients to avoid alcohol because of worsening drowsiness, dizziness, impaired judgment, and the potential to aggravate the underlying mood or anxiety disorder.
alcoholvenlafaxineeffexorsnriantidepressantblood pressurecns depressantdepressionanxiety