1 interaction related to edamame
Edamame is whole young soybeans. Soy protein and isoflavones can bind levothyroxine in the gut and modestly reduce how much is absorbed if the two are taken close together. The evidence is limited and mixed: case reports and one pharmacokinetic study suggest a small reduction in absorption, while the only randomized crossover study found no significant effect. Any impact is best avoided simply by separating the dose from soy-rich meals.
