1 interaction related to dietary fat
Vitamins A, D, E, and K depend on bile-driven micelle formation in the small intestine to be absorbed, and that process is triggered by dietary fat. Taking these vitamins with a fat-free meal or on an empty stomach reduces how much you absorb, while taking them with a meal that contains some fat improves absorption. Controlled studies in vitamin D show meaningfully greater absorption when the supplement is taken with fat.