dairy
4 interactions related to dairy
doxycycline + calcium
Calcium binds doxycycline in the gut, forming a complex the body cannot fully absorb. Taking doxycycline together with calcium supplements, calcium-based antacids, or large dairy servings can lower how much antibiotic reaches the bloodstream, though doxycycline binds calcium less than older tetracyclines.
tetracycline + calcium
Calcium binds to tetracycline in the gut, forming an insoluble chelate that the intestine cannot absorb. Dairy products, calcium supplements, and calcium-based antacids can sharply reduce how much tetracycline reaches your bloodstream, which can drop levels below what is needed to treat the infection.
dairy + digoxin
Dairy is a dietary source of calcium, and calcium status modestly influences how digoxin acts on the heart. The dietary-dairy effect is minor on its own; the more relevant scenario is large stacked calcium loads (dairy plus supplements plus calcium-containing antacids) or intravenous calcium in a hospital setting. Milk proteins may also slightly reduce digoxin absorption from oral doses, but the effect is small and usually not clinically meaningful.
dairy + fluoroquinolones
Calcium and other metal ions in dairy products bind oral fluoroquinolone antibiotics in the gut, forming poorly absorbed chelate complexes that lower the amount of antibiotic reaching the bloodstream.