cruciferous
3 interactions related to cruciferous
cabbage + levothyroxine
Cabbage and other brassica vegetables release thiocyanates and goitrin that can compete with iodide uptake at the thyroid and interfere with hormone synthesis. In normal, mostly-cooked portions this has no meaningful effect on levothyroxine in iodine-sufficient adults. Concern is limited to very large, sustained raw-cruciferous intakes or iodine-poor diets.
broccoli + warfarin
Broccoli is one of the most vitamin K1 (phylloquinone)-rich common vegetables, and vitamin K is the cofactor warfarin works by blocking. It is not about avoiding broccoli but about consistency: large swings in intake can move your INR and reduce warfarin's effect or raise bleeding risk.
cauliflower + levothyroxine
Cauliflower is a cruciferous vegetable whose breakdown products (thiocyanates) can theoretically compete with iodine uptake by the thyroid. In practice, a 2024 systematic review found brassica vegetables at normal dietary intakes do not impair thyroid function when iodine is adequate, and because levothyroxine is hormone you swallow as a tablet, ordinary cauliflower portions do not meaningfully affect it.
