1 interaction related to cox-2
Curcumin and ginger both inhibit NF-kB and COX-2 signaling, but ginger also independently blocks 5-lipoxygenase and contains gingerols and shogaols that suppress prostaglandin and leukotriene synthesis. A randomized trial of a turmeric-black pepper-ginger combination showed efficacy comparable to naproxen for chronic knee osteoarthritis pain.