cofactor
2 interactions related to cofactor
vitamin b1 + magnesium
Magnesium is the required cofactor that converts thiamine (vitamin B1) into its active coenzyme form, thiamine pyrophosphate (TPP). Without adequate magnesium, thiamine cannot activate properly, so supplementing thiamine in a magnesium-deficient person produces little benefit until magnesium is restored.
thiaminevitamin b1magnesiumtppenergy metabolismcofactorwernickesynergy
nac + selenium
NAC supplies cysteine for glutathione synthesis while selenium is the obligate cofactor in glutathione peroxidase enzymes, which use glutathione to neutralize peroxides. Without adequate selenium, the glutathione that NAC helps produce cannot be fully utilized in peroxide detoxification.
nacseleniumglutathione peroxidaseantioxidantdetoxliversynergycofactor