1 interaction related to clonazepam
Clonazepam is a benzodiazepine that calms the brain by enhancing GABA, its main inhibitory neurotransmitter. Passionflower appears to act on the same GABA system and may increase the sedative effect of benzodiazepines. Taken together, the most likely result is additive drowsiness. The human evidence is limited and mostly suggestive, so this is best treated as a caution rather than a proven hazard.