1 interaction related to clarithromycin
Clarithromycin is a strong CYP3A4 inhibitor. Red yeast rice's active compound, monacolin K, is chemically identical to the statin lovastatin and is cleared mainly by CYP3A4. Combining them slows clearance of the statin-like compound and raises its blood levels, increasing the risk of muscle injury and, rarely, rhabdomyolysis.
