ciprofloxacin
5 interactions related to ciprofloxacin
antibiotics + calcium
Calcium can bind to certain antibiotics (tetracyclines and fluoroquinolones) in the gut and reduce how much of the drug is absorbed.
antibiotics + probiotics
Taken at the same moment, an antibiotic can kill bacterial probiotic organisms before they reach the gut, lowering the probiotic's benefit. Spacing the doses apart fixes it.
caffeine + ciprofloxacin
Ciprofloxacin inhibits the liver enzyme CYP1A2, which is the main pathway that clears caffeine. As a result, caffeine is broken down more slowly, its blood levels stay higher for longer, and its stimulant effects are amplified and prolonged while you are on the antibiotic.
dairy + fluoroquinolones
Calcium and other metal ions in dairy products bind oral fluoroquinolone antibiotics in the gut, forming poorly absorbed chelate complexes that lower the amount of antibiotic reaching the bloodstream.
coffee + ciprofloxacin
Ciprofloxacin inhibits CYP1A2, the liver enzyme that clears caffeine, slowing caffeine metabolism so a normal amount of coffee produces higher, longer-lasting caffeine levels and stronger stimulant effects.