1 interaction related to cholecalciferol
Vitamin D's active metabolite (calcitriol) can mildly induce CYP3A4, the liver enzyme that breaks down atorvastatin, which can lower atorvastatin blood levels. Despite this, the cholesterol-lowering effect appears largely preserved, so the combination is generally fine. Strip precise dose targets and review high-dose vitamin D regimens with your doctor or pharmacist.