chlorogenic acid
2 interactions related to chlorogenic acid
levothyroxine + coffee
Coffee, including espresso and instant coffee, can reduce levothyroxine absorption by roughly 25 to 55 percent when consumed at the same time as the tablet. Chlorogenic acids and tannins in coffee appear to bind levothyroxine and the acidic environment may also alter dissolution and gastric emptying.
levothyroxinecoffeeabsorptionthyroidcaffeinetiminghypothyroidismchlorogenic acid
coffee + iron
Coffee contains chlorogenic acid and other polyphenols with galloyl groups that chelate non-heme iron in the gut lumen, forming insoluble complexes. A cup of coffee taken with a meal can reduce non-heme iron absorption by roughly 39% to 60%.
coffeeironabsorptionanemiapolyphenolschlorogenic acidnon-heme irontiming