carotenoid
2 interactions related to carotenoid
lycopene + fat
Lycopene is a fat-soluble carotenoid whose absorption depends on incorporation into bile-acid micelles, which require dietary fat. Human studies show that eating lycopene-rich foods with a fat source — such as olive oil or avocado — substantially increases how much lycopene reaches the bloodstream.
lycopenefatolive oiltomatocarotenoidabsorptionsynergybioavailability
alcohol + vitamin a
Alcohol depletes the liver's vitamin A by inducing cytochrome P450 enzymes (notably CYP2E1) that break retinol down into toxic byproducts. Adding high-dose vitamin A or beta-carotene supplements on top of regular drinking can worsen liver injury rather than correct the deficiency, so repletion in drinkers is not as simple as taking a pill.
alcoholvitamin aretinolbeta caroteneliver diseasehepatotoxicitycyp2e1carotenoid