1 interaction related to caramboxin
Star fruit (Averrhoa carambola) contains caramboxin, a neurotoxin that excites neurons, plus soluble oxalates that can injure the kidneys. In people with reduced kidney function, who cannot clear caramboxin, eating star fruit has triggered intractable seizures and status epilepticus. This is the fruit's own toxicity rather than a chemical reaction with phenytoin, but for someone taking phenytoin to prevent seizures it adds a serious, avoidable risk.
