capsaicin
2 interactions related to capsaicin
cayenne + warfarin
Capsaicin, the active constituent in cayenne (Capsicum), is theorized to add modestly to warfarin's blood-thinning effect through additive antiplatelet activity and possible effects on drug metabolism. The interaction is mechanistic; no human bleeding cases specific to cayenne plus warfarin have been documented, and interaction databases classify it as minor.
cayenne + ace inhibitors
Capsaicin, the active compound in cayenne, acts on the same airway cough receptors that ACE inhibitors sensitize, so it may trigger or worsen the dry cough some people get on ACE inhibitor therapy. The evidence is a single older case report plus consistent mechanism; the effect is a nuisance, not a danger, and cayenne does not reduce how well the medication works.