breast cancer
2 interactions related to breast cancer
hrt + soy isoflavones
Soy isoflavones (genistein, daidzein) act as selective estrogen receptor modulators with preferential binding to ER-beta. Combining high-dose isoflavone supplements with prescribed hormone replacement therapy adds an additional estrogenic signal of uncertain magnitude, which is most concerning for women with a history of estrogen-sensitive cancer.
hrthormone replacement therapysoy isoflavonesgenisteindaidzeinphytoestrogenmenopausebreast cancer
estrogen + dong quai
Dong quai (Angelica sinensis) shows estrogen-agonist activity in vitro and promotes growth of estrogen receptor-positive breast cancer cells. Combining it with prescribed estrogen therapy may add unwanted estrogenic stimulation, and dong quai's coumarin content increases bleeding risk in patients also on hormone therapy with VTE risk.
estrogendong quaiangelica sinensishormone replacementphytoestrogenbreast cancermenopauseherbal interaction