1 interaction related to black pepper
Piperine, the active alkaloid in black pepper, inhibits hepatic and intestinal glucuronidation of curcumin and other compounds, and a landmark human study reported a 2000% increase in curcumin bioavailability when 20 mg piperine was co-administered with 2 g curcumin. This is one of the most cited absorption-enhancement combinations in the supplement literature.