1 interaction related to betaine
Choline (via its metabolite betaine) and vitamin B12 power the two parallel pathways that remethylate homocysteine to methionine: the choline-betaine-BHMT route and the folate-B12-methionine-synthase route. Adequate choline can compensate for low B12 or folate status by maintaining methylation through the BHMT pathway, supporting healthy homocysteine and SAMe levels.