beta blocker

4 interactions related to beta blocker

alcohol + propranolol

Alcohol and propranolol can produce additive hypotension, dizziness, and sedation through combined vasodilation and central nervous system depression; propranolol also masks the warning symptoms of low blood sugar and rapid heart rate. Chronic heavy drinking induces hepatic enzymes and can reduce propranolol effectiveness.

moderate
alcoholpropranololbeta blockerhypotensiondizzinessinderalblood pressureheart rate

caffeine + propranolol

Caffeine raises systemic vascular resistance and heart rate, partially opposing propranolol's blood-pressure and heart-rate lowering effects. High caffeine intake can also worsen tremor and anxiety that propranolol is prescribed to treat.

low
caffeinepropranololbeta blockerhypertensionanxietytremorheart rateblood pressure

dark chocolate + blood pressure medications

Dark chocolate flavanols improve nitric-oxide-dependent vasodilation and modestly lower systolic and diastolic blood pressure (typically 2–3 mmHg). Combined with antihypertensives, this can additively lower blood pressure, occasionally producing symptoms of hypotension such as dizziness in sensitive patients.

low
dark chocolateblood pressureantihypertensivecocoa flavanolsnitric oxidehypotensionACE inhibitorbeta blockercalcium channel blocker

coffee + propranolol

Caffeine in coffee acutely raises heart rate and blood pressure, which can counteract the heart-rate and blood-pressure-lowering effects of propranolol, a non-selective beta-blocker. Propranolol may also slow caffeine clearance modestly, increasing caffeine exposure.

moderate
coffeepropranololbeta blockercaffeinehypertensionheart rateblood pressuredrug interaction