arb
5 interactions related to arb
losartan + potassium
Losartan blocks the angiotensin II receptor, lowering aldosterone and reducing renal potassium excretion in the same way ACE inhibitors do. Concurrent potassium supplementation can drive serum potassium into the hyperkalemic range, with cardiac arrhythmia risk in patients with kidney impairment, diabetes, or heart failure.
losartan + licorice
Glycyrrhizin in licorice mimics aldosterone, causing renal sodium and water retention and potassium loss. This pseudoaldosteronism raises blood pressure and counteracts losartan's antihypertensive effect, while also producing hypokalemia that can cause weakness and arrhythmia.
losartan + hawthorn
Hawthorn produces modest blood pressure lowering (roughly 5 to 11 mmHg systolic in clinical trials) through vasodilation and mild ACE-like activity. Combined with losartan, the additive effect could occasionally cause hypotension or dizziness, particularly in people on multiple antihypertensives or those starting hawthorn at high doses.
valsartan + spirulina
Spirulina has modest antihypertensive effects in clinical trials (systolic drop of around 4-5 mmHg) and contains roughly 14 mg of potassium per gram. Combined with valsartan, theoretical risks include additive blood pressure lowering and a minor contribution to potassium load, though at typical supplement doses neither effect is large.
valsartan + potassium
Valsartan is an angiotensin II receptor blocker that suppresses aldosterone and slows renal potassium excretion. The FDA-approved Diovan label specifically warns that potassium supplements and potassium-containing salt substitutes may lead to clinically significant hyperkalemia, particularly in patients with renal impairment, diabetes, or heart failure.