anti-inflammatory
4 interactions related to anti-inflammatory
omega-3 + curcumin
Omega-3 fatty acids (EPA and DHA) and curcumin both reduce inflammation through complementary pathways — omega-3s alter cell membrane composition and produce specialized pro-resolving mediators, while curcumin directly inhibits NF-kB and inflammatory cytokine signaling.
vitamin c + quercetin
Quercetin is a flavonoid with antioxidant, anti-inflammatory, and antiviral activity; vitamin C 'recycles' oxidized quercetin back to its active form, prolonging its effect and preventing prooxidant byproducts. The combination has been studied for immune support and antiviral effects.
curcumin + quercetin
Quercetin inhibits the same UDP-glucuronosyltransferase and CYP3A4 enzymes that rapidly metabolize curcumin, raising its plasma exposure, and both polyphenols share complementary anti-inflammatory and antioxidant pathways. In vitro intestinal models and animal studies show the combination increases apical-to-basal uptake of curcumin and amplifies NF-kB pathway suppression.
quercetin + bromelain
Bromelain is a proteolytic enzyme complex from pineapple that improves quercetin absorption (reportedly 2-3x) and adds independent anti-inflammatory effects (fibrinolytic activity, COX modulation, bradykinin reduction). The pair is commonly co-formulated for inflammation, allergy, and immune support.