anti-inflammatory
4 interactions related to anti-inflammatory
omega-3 + curcumin
Omega-3 fatty acids (EPA and DHA) and curcumin lower inflammation through complementary pathways — omega-3s remodel cell membranes and generate specialized pro-resolving mediators, while curcumin inhibits NF-kB and downstream inflammatory cytokine signaling. Human trials in migraine patients show the combination can reduce inflammatory markers more than either alone.
vitamin c + quercetin
Quercetin is a plant flavonoid with antioxidant and anti-inflammatory activity. As quercetin scavenges free radicals it becomes oxidized, and vitamin C can donate electrons to recycle it back to its active form, theoretically prolonging its effect and limiting prooxidant byproducts. This pairing is popular for immune and allergy support, but the human evidence is limited and largely mechanistic.
curcumin + quercetin
In laboratory intestinal-cell models, quercetin slows the gut and liver enzymes (UDP-glucuronosyltransferase and CYP3A4) that normally break curcumin down quickly, which raised curcumin's measured permeability across the cell layer. Both polyphenols also act on overlapping anti-inflammatory and antioxidant pathways. The evidence is mechanistic and limited to in vitro work — no human trials have confirmed a real-world bioavailability or anti-inflammatory benefit from combining them.
quercetin + bromelain
Quercetin and bromelain are commonly co-formulated for inflammation and allergy support, and bromelain has its own anti-inflammatory action, but the popular claim that bromelain boosts quercetin absorption 2-3x is a vendor figure not backed by any human pharmacokinetic study.
