alpha-lipoic acid
2 interactions related to alpha-lipoic acid
metformin + alpha-lipoic acid
Alpha-lipoic acid (ALA) can improve insulin sensitivity and modestly lower blood glucose, producing an additive hypoglycemic effect with metformin. Most short-term clinical studies show the effect is mild, but susceptible patients (elderly, undernourished, on beta-blockers) can experience symptomatic lows.
metforminalpha-lipoic acidaladiabetesneuropathyhypoglycemiablood sugarsupplement interaction
milk thistle + alpha-lipoic acid
Silymarin from milk thistle stabilizes hepatocyte membranes and inhibits toxin uptake while alpha-lipoic acid regenerates intracellular glutathione and recycles vitamins C and E. Their hepatoprotective mechanisms are complementary rather than overlapping.
milk thistlesilymarinalpha-lipoic acidalaliverhepatoprotectiveantioxidantdetox