ala
7 interactions related to ala
metformin + alpha-lipoic acid
Alpha-lipoic acid (ALA) can improve insulin sensitivity and modestly lower blood glucose, producing an additive hypoglycemic effect with metformin. Most short-term clinical studies show the effect is mild, but susceptible patients (elderly, undernourished, on beta-blockers) can experience symptomatic lows.
milk thistle + alpha-lipoic acid
Silymarin from milk thistle stabilizes hepatocyte membranes and inhibits toxin uptake while alpha-lipoic acid regenerates intracellular glutathione and recycles vitamins C and E. Their hepatoprotective mechanisms are complementary rather than overlapping.
flax seeds + warfarin
Flax seeds are high in alpha-linolenic acid (an omega-3 fatty acid) that can mildly inhibit platelet aggregation, and their soluble fiber and lignans can slow warfarin absorption when taken at the same time. Combined, these effects can shift INR in either direction, with case-level reports of altered anticoagulation.
chia seeds + warfarin
Chia seeds are high in alpha-linolenic acid (an omega-3 fatty acid) and soluble fiber. Omega-3 intake at high doses may mildly inhibit platelet aggregation and could theoretically enhance warfarin's anticoagulant effect, while the soluble fiber may also blunt warfarin absorption when taken at the same time.
flaxseed + warfarin
Flaxseed contains alpha-linolenic acid that can mildly reduce platelet aggregation and may add to warfarin's bleeding risk, particularly at high supplemental doses. Flaxseed is also very high in soluble fiber, which can bind warfarin in the gut and erratically reduce its absorption.
walnuts + warfarin
Walnuts contain only trace amounts of vitamin K (about 2.7 mcg per 100 g) and small quantities of plant-based omega-3 (alpha-linolenic acid). Typical servings are unlikely to meaningfully shift INR, but dramatic changes in intake or very large daily portions could theoretically nudge anticoagulation in either direction.
chia seeds + blood thinners
Chia seeds are high in plant-form omega-3 (alpha-linolenic acid) and soluble fiber, both of which can mildly reduce platelet aggregation and theoretically add to the bleeding risk of warfarin, DOACs, aspirin, and antiplatelet drugs. The Drugs.com chia monograph explicitly flags caution with anticoagulants based on case reports for related species.