aging
2 interactions related to aging
acetyl-l-carnitine + alpha-lipoic acid
Acetyl-L-carnitine shuttles fatty acids into mitochondria for energy production while alpha-lipoic acid acts as a mitochondrial antioxidant and cofactor for energy-producing enzymes; in aged animal studies, the combination reversed mitochondrial decay and improved memory more than either alone.
acetyl-l-carnitinealpha-lipoic-acidmitochondriaagingcognitionantioxidantenergysynergy
fisetin + quercetin
Fisetin and quercetin are structurally related flavonols with overlapping but distinct senolytic and anti-inflammatory mechanisms. Fisetin was identified in a Mayo Clinic screen as the most potent natural senolytic, while quercetin has been clinically tested as part of the dasatinib + quercetin senolytic combination, and the two together broaden the senolytic and antioxidant coverage.
fisetinquercetinsenolyticflavonoidlongevitysenescenceagingsynergypolyphenol