adhd
4 interactions related to adhd
adderall + st. john's wort
Adderall (mixed amphetamine salts) raises synaptic norepinephrine, dopamine, and to a lesser extent serotonin. St. John's Wort inhibits reuptake of those same monoamines. Together they can push the serotonergic system far enough to risk serotonin syndrome and can add cardiovascular strain. Separately, St. John's Wort strongly induces the CYP3A4 enzyme and P-glycoprotein, which can blunt the effect of many co-taken medicines.
methylphenidate + st. john's wort
Methylphenidate treats ADHD by inhibiting reuptake of dopamine and norepinephrine. St. John's Wort adds its own monoamine reuptake activity and is a strong inducer of the CYP3A4 drug-metabolising enzyme. A small published observation suggests St. John's Wort can blunt methylphenidate's effect on ADHD symptoms. There is also a theoretical, additive serotonergic risk, mainly relevant if other serotonergic drugs are present, but no confirmed serotonin syndrome cases have been reported for this specific pair.
energy drinks + adderall
Energy drinks deliver caffeine alongside other stimulant ingredients such as taurine and guarana, producing additive sympathomimetic effects on top of the amphetamine salts in Adderall. Both raise heart rate, blood pressure, and adrenergic activity, which can bring on palpitations, elevated blood pressure, anxiety, and insomnia, and in rare cases more serious heart rhythm disturbances.
caffeine + adderall
Caffeine and the amphetamine salts in Adderall are both sympathomimetic stimulants. Taking them together adds their effects, so heart rate, blood pressure, jitteriness and trouble sleeping tend to be more pronounced than with either alone.